Don P. Wolf and Mary Zelinski-Wooten provide a comprehensive review of the procedures and techniques used in assisted reproduction, as well as in nuclear transfer for both the treatment of human infertility and the propagation of animals. Combining the details of clinical application with the physiological facts of reproduction, the authors treat subjects such as the in vitro maturation of oocytes, embryo culture, intracytoplasmic sperm injection, and the process of nuclear transfer. Cutting-edge and wide-ranging, Assisted Fertilization and Nuclear Transfer in Mammals offers clinical ARTs practitioners, research scientists, those responsible for animal care, and students not only an informative historical perspective on the development of ARTs, but also updates on several of the more dynamic clinical areas, and a highly practical understanding of their applications.
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Though these 17 contributed chapters are divided into sections on assisted reproduction and nuclear transfer, the controversial field of assisted reproductive technology (ART) is treated as a continuum since assisted reproduction lays the technical groundwork for asexual reproduction by nuclear transfer. Addressing a wide audience of clinical ART practitioners, students, research scientists, and animal caretakers, specialists provide a historical overview of mammalian in vitro fertilization (IVF) and discuss the latest technical aspects of IVF and cloning (Dolly is mentioned). An especially intriguing application is preservation of endangered species. Includes ultrasound images, photomicrographs of eggs at different stages of nuclear maturation, and color three-dimensional mathematical models of follicular development. Wolf and Zelinski- Wooten are with the Oregon Regional Primate Research Center in Beaverton, OR (which has drawn protests from animal rights activists). Annotation c. Book News, Inc., Portland, OR (booknews.com)
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