Description
Presents the techniques currently used for studying the disease virus, ranging from detecting the anti-virus in serum and the serum itself in liver tissue, to genotypes and detecting and quantifying the virus in serum. Also evaluates recombinant proteins in immunological test systems, including identifying important antigenic epitopes, antibodies, and recombinant antigens. Among the highlights are step- by-step instructions for key assays, using liver transplant recipients infected by the virus as a model for studying pathogenesis, pharmacological and clinical principles in studying drugs against it, and molecular diagnostic resources on the Internet. Annotation c. by Book News, Inc., Portland, Or.
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Johnson Lau and his expert collaborators present cutting-edge techniques for study of the hepatitis C virus, a disease afflicting over 100 million people worldwide. The methods range from the detection of anti-HCV in serum and HCV in liver tissue to HCV genotypes and the detection and quantification of HCV in serum. In addition to these key protocols, the authoritative contributors also evaluate recombinant proteins in immunological test systems, including the identification of important antigenic epitopes, antibodies, and recombinant antigens. The methods and systems detailed in this book will play a key role in the development of more effective antivirals, in the introduction of vaccines, and in a deeper understanding of viral replication strategies, viron structure, and the mechanisms of viron assembly and release.
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