Reports on advances in the field of dendritic cell biology. Material is in sections on the origin of dendritic cells, dendritic cells in the periphery, dendritic cells and interaction with other cells, dendritic cells in disease, dendritic cell-based therapies, and techniques and other topics in dendritic cell biology. Specific topics include intestinal dendritic cells, NK cells, Langerhans cell migration and cellular interactions, dendritic cells in autoimmunity, allergy, and genetic engineering of dendritic cells. Includes color micro-images and diagrams. Lotze is affiliated with the departments of surgery and molecular genetics and biochemistry at the University of Pittsburgh Cancer Institute. Thomson is affiliated with the departments of surgery and molecular genetics and biochemistry, and with the Thomas E. Starzl Transplantation Institute, at the University of Pittsburgh. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Dendritic Cells is the first definitive book on this subject, and brings together the most current information in the field for scientists and clinicians. It outlines research studies, the first reports of therapeutic applications of dendritic cells, and the enormous potential of these unique cells. Contributors are from the key research groups around the world who are working on the immunobiology of dendritic cells and in applied areas, striving to develop their therapeutic potential.Key Features* First book on the subject of dendritic cells, the most powerful tool for manipulating the immune system* Discusses the origin of DCs, their function throughout the body, and how they interact with other cells* Covers the role of DCs in cancer, infectious diseases, transplantation, autoimmunity, and more* Reports on novel therapeutic strategies, including cellular vaccines and tolerance induction* Includes internationally-acclaimed contributors including Jacques Banchereau and Ralph Steinman* Contains a spectacular 32-page color plate section
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