Description
The first edition was published in 1977, and the second and third in 1983 and 1987. Like its predecessors, the fourth edition provides information on both theoretical aspects and practical test methods, including both in vivo and in vitro approaches, but now displaying increased attention to the latter in keeping with a worldwide movement for the development of suitable alternatives to animals when feasible. The book blends fundamental information on the mechanisms of action of toxicants on skin, the varied responses of skin to specific toxicants, and approaches to evaluating dermal toxicity. Annotation copyright Book News, Inc. Portland, Or.
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A guide to the field of dermatotoxicology. This edition includes fundamental information on the mechanisms of action of toxic substances on skin as well as practical information on the varied responses of skin to specific toxic substances and approaches to evaluating dermal toxicity. Other topics discussed include: hostile natural elements, such as ultraviolet radiation, poisonous plants, man-made detergents and chemicals; problems associated with chronic occupational skin exposure to toxic chemicals; animal alternative research programmes; carcinogenic and Photo Carcinogenic Potential Of Xenobiotic Chemicals; Oculotoxicity; Risk assessment and management; and cosmetic safety.
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