Description
Introduces experienced geneticists and molecular biologists to the methodology and rationale of mapping genomes and whole chromosomes. Discusses such topics as the organization and structure of genomes, subdividing them, assembling a physical map, and finding genes in large genomes. Updated from the 1995 edition with a new chapter on analyzing sequence data, and the field's literature to September 1997. Annotation c. by Book News, Inc., Portland, Or.
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Genome analysis and genomics are at the forefront of current research in the life sciences. Since the first edition of Principles of Genome Analysis was published, the sequencing of genomes has continued apace, with the major landmark of the human genome sequence being achieved in 2001. Now the emphasis of biological research is on genomics: the understanding of gene function and the interaction of gene products at the whole genome level.As before, this book provides a step-by-step outline of the techniques involved in genome mapping and sequencing. Additionally, the text has been greatly expanded to cover sub-disciplines of genomics, revisions of sections on genome sequencing and bioinformatics, and new chapters on comparative genomics, functional genomics and proteomics. The book concludes with an exciting new chapter describing a variety of ways to utilize genome analysis and sequencing in biology, medicine and agriculture.Aimed at advanced undergraduates, this text will follow the same format as the highly successful Principles of Gene Manipulation by Primrose, Twyman and Old, now in its sixth edition.
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