Description
While the previous editions of this work were based entirely on a format consisting of problem-based learning cases, Korf (genetics, U. of Alabama) has conceded that some didactic chapters would improve student understanding of basic concepts. For this edition then, he has chosen to open with didactic discussion of DNA structure and function, genetic variation, patters of inheritance, the human genome, multifactorial inheritance, cell division and chromosomes, population genetics, and cancer genetics. These chapters are followed by problem- based learning cases dealing with chromosome translocation, molecular diagnosis, newborn screening, developmental genetics, carrier screening, genetic risk assessment, genetic testing for risk of cancer, pharmacogenetics, and gene therapy. Also new to this edition is a greater attention to genomics, which concerns larger scale analysis than traditional genetics and has become increasingly important in medical practice. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)
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This text clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions. A newly expanded Part 1, Basic Principles of Human Genetics, focuses on introducing the reader to key concepts such as Mendelian principles, DNA replication and gene expression.Part 2, Genetics and Genomics in Medical Practice, uses case scenarios to help you engage with current genetic practice. Now featuring full-color diagrams, Human Genetics and Genomics has been rigorously updated to reflect today's genetics teaching, and includes updated discussion of genetic risk assessment, single gene disorders and therapeutics. Key learning features include: Clinical snapshots to help relate science to practice 'Hot topics' boxes that focus on the latest developments in testing, assessment and treatment 'Ethical issues' boxes to prompt further thought and discussion on the implications of genetic developments 'Sources of information' boxes to assist with the practicalities of clinical research and information provision.
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