Description
Editors Zigmond, Rowland, and Coyle introduce this neuropathology reference with an overview addressing lesion localization, imaging, neuronal vulnerability, stem cells, animal research and clinical trials, and biomarkers and genetics of disease. Five sections are then presented, each with a section introduction followed by chapters reviewing the known etiology, presentation, and clinical management of specific disorders. These sections discuss developmental disorders such as ADHD, the autism spectrum, and chromosome disorders; diseases of the peripheral nervous system; central nervous system dysfunction and degeneration including spinal cord injury, epilepsy, ALS, Parkinson’s, Huntington’s, Alzheimer’s, and stroke; inflammation, infection, and autoimmune impacts on the nervous system; and pathologies of higher function including anxiety and mood disorders, addiction, schizophrenia, and migraine. The final section discusses neurological disease in relation to social factors and research ethics. Annotation ©2015 Ringgold, Inc., Portland, OR (protoview.com)
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Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases.
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