Updated to reflect the wide spectrum of economic, regulatory, financial, ethical, and political issues impacting vaccinology in industrialized and developing nations, the Third Edition pinpoints relevant breakthroughs, trends, and advances in vaccinology and immunization science. The book highlights the most influential developments in vaccine safety, regulation, manufacture, and utilization, as well as clinical trials standardization and monitoring. With contributions from a renowned team of specialists and researchers, this reference tracks the technologies, experimental studies, and international programs that will revolutionize and transform the world of vaccinology in the 21st century.
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After a brief historical perspective, Levine (School of Medicine, University of Maryland) introduces the technologies involved in the creation of the new generation of vaccines, covering not only the technologies of the biotechnology revolution but also toxicological studies, phased clinical trials, evaluation of efficacy, cataloging of adverse events, and measurement of impact. Major international programs supporting more widespread use of vaccines are described, and the role of regulatory authorities is outlined. Chapters on specific diseases are divided into sections on diseases for which vaccines are in place, those diseases for which vaccines do not yet exist, vaccines against cancer and other chronic diseases and vaccine therapy, and vaccines against bioterror agents. This third edition reflects changes in the field since the second edition was published in 1997. Annotation ©2004 Book News, Inc., Portland, OR (booknews.com)
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