Description
The 17 papers cover nucleic acid aspects and synthetic gene delivery systems. Among the specific topics are synthetic retrotransposon vectors and gene targeting, replicating plasmid vectors for cancer gene therapy, the application of electronic pulse delivery, self-assembling DNA photonic nanostructures, nonviral systems, targeting nucleic acids to the liver, ligand- polylysine mediated gene transfer, and the proton sponge as a trick the viruses did not exploit. Reproduced from typescripts. Annotation c. by Book News, Inc., Portland, Or.
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Discusses recent advances in artificial self-assembling systems, including retrotransposon vectors, hairpin ribozymes, triple-helix-forming oligonucleotides, liposome-mediated transfection, and photonic nanostructures. Addresses developing efficient synthetic vectors such as modular self-assembling systems mimicking important features of viral vectors. Presents new developments in synthetic self-assembling gene delivery systems, including innovations in nonviral systems, targeting nucleic acids, ligand-polylysine mediated transfer, dendrimer-mediated transfection, cationic liposomes, and polylysine DNA complexes.
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