microRNA: Biology, Function & Expression (Nuts & Bolts series)
Books / Hardcover
Books › Science › Life Sciences › Biology › Microbiology
ISBN: 1933255196 / Publisher: Dna Press, August 2006
Providing a comprehensive overview of a fast-emerging field, this description of the biological role of microRNAs discusses methods for identifying and characterizing their functions and looks at potential applications of microRNA research in medicine and pharmacology. First identified a decade ago, microRNAs (miRNAs) are small, noncoding RNA molecules that appear to regulate gene expression. Found in plant and animal species and possibly traceable back to ancient forms of life, miRNAs are now estimated to regulate a third or more of human genes.
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Sixteen chapters review the methods and results of characterizing the function of small, noncoding RNA molecules that appear to serve as negative regulators of gene expression in plants and animals. Topics include RNA-induced silencing complex (RISC) biology, virus- encoded microRNAs, involvement in stem cell division, the miRBase database, and computational prediction of microRNA targets. The contributors are a mixture of researchers working for private laboratories, particularly GlaxoSmithKline, and public universities. Distributed by the Independent Publishers Group. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)
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