Best friends Jane Rizzoli and Dr. Maura Isles, a detective and a medical examiner, work together to solve homicides.
"Homicide detective Jane Rizzoli (Angie Harmon) and forensic pathologist Maura Isles (Sasha Alexander) are close friends, complete opposites and on the case in all 15 gritty episodes based on the best-selling novels by Tess Gerritsen. Season Two sees brash Jane healing emotional and physical scars as old loves re-appear and her mother Angela (Lorraine Bracco) deals with divorce. Meanwhile Jane’s ex-con brother Tommy (Colin Egglesfield) has eyes for cerebral Maura, whose own family life is complicated by her adoptive mother Constance (Jacqueline Bisset) and a biological dad with a link to the Mob. And in an explosive season finale, Jane must choose between her job and Maura. Can the friendship survive?"